Year 2015; Volume 1; Issue 4

Comparison of Effects of Adding Dexmedetomidine as an Adjuvant to Intrathecal 0.5% Bupivacaine versus Fentanyl in Gynaecological Procedures

Author: Dr. Pradeep Dhumane* and Dr. Madhushalini

Department of anaesthesia, Government Medical College, Nagpur, Maharashtra, India-440021

Aim and Objectives: The present study was undertaken to compare the characteristics of spinal block, hemodynamic effect and postoperative analgesia of dexmedetomidine or fentanyl given intrathecally with 0.5% bupivacaine for spinal anesthesia. Methods: 76 female patients age between 30-60 years classified as ASA grade I and II were randomly divided into two equal groups scheduled for vaginal hysterectomy and vaginal wall repair. Group I received 15 mg 0.5% bupivacaine with 25ugm of fentanyl and Group II received 15mg of 0.5% bupivacaine with 5ugm of dexmedetomidine. The total volume injected was 3.5 ml in both groups. All the parameters were recorded. Results: The group II had early onset of sensory and motor block as compared to group I. The duration of sensory and motor block was significantly prolonged in group II than group I. The postoperative analgesia was significantly longer in group II as compare to group I with minimal postoperative side effects. Group II provides stable hemodynamic condition as compare to group I. Conclusion: The 5 μg dexmedetomidine seem to be an attractive alternative to 25 μg Fentanyl as an adjuvant to spinal bupivacaine in vaginal hysterectomy patients.
Keywords: Dexmedetomidine, Fentanyl, Bupivacaine, Sensory and motor blockade, postoperative analgesia, hysterectomy.

Dr. Pradeep Dhumane*
Department of anaesthesia, Government Medical College, Nagpur, Maharashtra, India-440021
Article Type : Research Article
Date : 2015-09-29
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